About WJ Mooi

W.J. (Wolter) Mooi was born in Groningen, 1956. After studying medicine at the University of Leiden, and pathology at the Universities of Amsterdam and London, Wolter obtained his registration as consultant pathologist and his PhD degree (University of Amsterdam) in 1986. He joined the Netherlands Cancer Institute as research fellow, consulant pathologist and head of the Department of Pathology. Professorships at the VU University  Amsterdam (1991) and the Erasmus University of Rotterdam (1996) followed. After a period of four years as head of department at Erasmus University Rotterdam, Wolter went back to Amsterdam, where is was appointed professor of pathology at the University of Amsterdam and, for the second time, at the VU University of Amsterdam, where he is now stationed and divides his time between surgical pathology, undergraduate teaching and research.

Wolter is (co-) author of 171 peer-reviewed articles, 3 monographs and numerous chapters on various topics of melanocytic and pulmonary pathology. He is laureate of various pathological societies, and in 2011 he was chosen, among 2000 competitors, as teacher of the year of VU University Amsterdam.

Wolter is married to Hanneke Lavrijsen; they have two children, Remko and Marieke, both undergraduate students. In his spare time, Wolter enjoys classical music (being an active cello player), reading (favourite author: Thomas Mann), walking, photographing (snapshots: Málaga Breakfast, New Year's Day and Imitation Roses, 2011, middle right) and painting (Without Title, 1986, lower right; click on images to enlarge).

Wolter Mooi's most cited scientific articles:

1: Vredeveld LC, Possik PA, Smit MA, Meissl K, Michaloglou C, Horlings HM, Ajouaou A, Kortman PC, Dankort D, McMahon M, Mooi WJ, Peeper DS. Abrogation of BRAFV600E-induced senescence by PI3K pathway activation contributes to melanomagenesis. Genes Dev 2012; 26: 1055-69.

2: Kuilman T, Michaloglou C, Mooi WJ, Peeper DS. The essence of senescence. Genes Dev 2010; 24: 2463-79.

3: Kuilman T, Michaloglou C, Vredeveld LC, Douma S, van Doorn R, Desmet CJ, Aarden LA, Mooi WJ, Peeper DS. Oncogene-induced senescence relayed by an interleukin-dependent inflammatory network. Cell 2008; 133: 1019-31.

4: Michaloglou C, Vredeveld LC, Mooi WJ, Peeper DS. BRAF(E600) in benign and malignant human tumours. Oncogene 2008; 27: 877-95.

5: Mooi WJ, Peeper DS. Oncogene-induced cell senescence--halting on the road to cancer. New Engl J Med 2006; 355: 1037-46.

6: Michaloglou C, Vredeveld LC, Soengas MS, Denoyelle C, Kuilman T, van der Horst CM, Majoor DM, Shay JW, Mooi WJ, Peeper DS. BRAFE600- associated senescence-like cell cycle arrest of human naevi. Nature 2005; 436: 720-4.

7: Meuwissen R, Linn SC, Linnoila RI, Zevenhoven J, Mooi WJ, Berns A. Induction of small cell lung cancer by somatic inactivation of both Trp53 and Rb1 in a conditional mouse model. Cancer Cell 2003; 4: 181-9.

8: Krimpenfort P, Quon KC, Mooi WJ, Loonstra A, Berns A. Loss of p16Ink4a confers susceptibility to metastatic melanoma in mice. Nature 2001; 413: 83-6.

9: Mooi WJ. The advantage of rearranging bcl-6. New Engl J Med 1994; 331: 1459-60.

10: Slebos RJ, Kibbelaar RE, Dalesio O, Kooistra A, Stam J, Meijer CJ, Wagenaar SS, Vanderschueren RG, van Zandwijk N, Mooi WJ, et al. K-ras oncogene activation as a prognostic marker in adenocarcinoma of the lung. New Engl J Med 1990; 323: 561-5.