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Clinical information

Case 30 Male, 6 years. Congenital pigmented papule, skin of lower arm

Show diagnosis & comments

Diagnosis:

Pigmented spindle cell naevus, congenital (in view of patietnt history)

Comments:

PIGMENTED SPINDLE CELL NAEVUS (REED NAEVUS)

  • Spitz naevus variant occurring predominantly in children, adolescents and young adults
  • Usually compact and densely cellular lesion
  • Large spindle cells, often containing much melanin pigment, but some examples are poorly pigmented
  • Junctional component forms nests, often confluent, resulting in irregular masses
  • Reactive epidermal hyperplasia
  • Transepidermal elimination of nests is common
  • Ascent of solitary cells is commonly present
  • Mitotic activity is commonly identified. Abnormal mitotic figures are not a feature.
  • Dermal component is commonly rather cellular and compact, but there is no deep extenstion into the dermis.
  • Often melanophages and round-cell inflammatory infiltrate
  • Overall, this densely cellular lesion has a regular appearance, devoid of sudden changes in cell type, architecture or reactive epidermal or dermal changes
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Dear {friend_name}, {url} I believe this website may be of interest to you. It is an Open Educational Resource, containing a large collection of digitized histologic slides with explanatory films and other materials, aimed at surgical pathologists, dermatopathologist and pathologists in training. This site is entirely based on consultation materials of professor Wolter Mooi, VU University Amsterdam, and can be used free of charge. Kind regards, {my_name}

Slide sets

  • Common acquired naevus
  • Spitz naevus and variants
  • Blue naevus and variants
  • Congenital naevus
  • Dysplastic naevus
  • Nonmelanocytic skin lesions; some DD's
  • Melanoma: general features
  • Melanoma subtypes
  • Extracutaneous melanocytic lesions
  • Extracutaneous nonmelanocytic pigmented lesions
  • Problems and pitfalls

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