Case 24 Female, 39 years. Skin of backShow diagnosis & comments
Spitz naevus (predominantly junctional, spindle cell type).
Classical case. The ascent and slight nuclear irregularities are entirely acceptable in view of all other findings. Conspicuous Kamino bodies.
(PREDOMINANTLY JUNCTIONAL SPINDLE CELL) SPITZ NAEVUS
- Occurs at all ages, predominantly in children, adolescents and young adults
- Spindle cell type is the most common Spitz naevus subtype in adolescents and adults
- Spindle cell spitz naevi in that age group are most common on extremities
- Vertical oval nestsat tghe derfmoepidermal junction; confluence of nests may result in iregular masses
- Usually, there are shrinkage artifacts surrounding junctional nests, and, to a lesser extent, between cells within the same junctional nest.
- Usually epidermal hyperplasia
- Transepidermal elimination of nests and some ascent of solitary cells may be seen.
- Ascending cells are commonly smaller than junctional ones
- Mitotic figures are usually small in number
- Overall, the architecture is regular (cellular features, arrangement of cells, type and degree of reactive changes). No abrupt changes in cell type or lesional architecture
- Pigment is often absent or scarce, but some examples contain more pigment.