Case 8 Female, 32 years. Irregular lesion, skin of upper legShow diagnosis & comments
Spitzoid superficial spreading melanoma.
This melanoma is exceedingly difficult to recognize as such. The overall architectural and cytological appearance suggests Spitz naevus. There is more ascent of lesional melanocytes than is usually seen at this age, and mitotic figures were identified at all levels of the lesion. The indented and grooved nuclei, with coarsened chromatin, are not quite right for Spitz naevus.
Regional lymh node metastases became clinically manifest 12 years later.