Case 29 Female, 34 years. Nodule, skin of armShow diagnosis & comments
Naevoid nodular melanoma
SMALL CELL NAEVOID MELANOMA
Small cell naevoid melanomas are sometimes underdiagnosed because of the small, naevoid cell type and the sometimes regular overall (verrucous or dome-shaped) appearance. Some are bulky, esepcially the ones arising in large congenital naevi, they display considerable mitotic activity and there may be subtle but abrupt variations in cellular features or lesional architecture. Ascent may or may not be present. These melanomas sometimes affect children; such childhood lesions appear to be most common on the scalp.
- Magro CM, Crowson AN, Mihm MC. Unusual variants of malignant melanoma. Mod Pathol. 2006 Feb;19 Suppl 2:S41-70.
- Barnhill RL. Childhood melanoma. Semin Diagn Pathol. 1998 Aug;15(3):189-94.