Case 6 Male, 13 years. Pigmented nodule, skin of backShow diagnosis & comments
Superficial spreading melanoma with naevus remnant
The lesion obviously is a melanoma (compact masses of highly atypical melanocytes; epidermal consumption; lack of so-called 'maturation' abrupt changes in cell phenotype from cell group to cell group; mitotic activity) and there is a small junctional naevus remnant at the side of the melanoma. At the centre of the melanoma, there is a granulomatous response to keratin, indicative of a response to destruction of a hair follicle.
Naevus remnants in or adjacent to melanoma are most commonly of the 'banal' naevus NOS type.