This website uses cookies. Read our privacy statement for more information. Do you agree with its use? Yes, I agree

MELANOCYTE PATHOLOGY.COM

a free
self-study website

Main navigation of MELANOCYTE PATHOLOGY.COM

  • Home
  • How to use this site
  • Introduction
  • Slide sets
  • Downloads
  • Testimonials
  • About WJ Mooi
achtergrond afbeelding

Clinical information

Case 3 Female, 63 years. Irregular pigmented lesion, skin of lower back.

Show diagnosis & comments

Diagnosis:

Dysplastic naevus

Comments:

DYSPLASTIC NAEVUS:

  •         Somewhat irregular pigmented macule, or pigment papule with macular periphery
  •         Sizes vary; largest examples may exceed 1 cm in diameter
  •         Junctional or compound melanocytic naevus
  •         Richly cellular junctional component
  •         Junctional nests irregularly spaced and shaped
  •         Rete ridges irregularly elongated and oriented, with bridging
  •         Subepidermal lamellar sclerosis ('lamellar fibroplasia')
  •         Nuclear pleomorphism and anisochromasia ('random atypia') of junctional component
  •         Dermal component usually small cell type, with pigmentation in all levels
  •         Dermal melanophages and perivascular lymphocytic infiltrates

Presence of many such dysplastic naevi, esepcially in association with history of melanoma, or family history of melanoma, indicates substantial melanoma risk and necessitates close follow-up. Most examples are, however, isolated lesions not associated with melanoma history. Melanoma risk appears to be slightly higher than in other individuals, but the difference is small and has no concrete consequence (apart from advice to avoid excessive UV exposure).

Previous case Next case Return to the "Dysplastic naevus" slide set
  • Tweet

Tell a friend:

Send Email

Tell a friend

Dear {friend_name}, {url} I believe this website may be of interest to you. It is an Open Educational Resource, containing a large collection of digitized histologic slides with explanatory films and other materials, aimed at surgical pathologists, dermatopathologist and pathologists in training. This site is entirely based on consultation materials of professor Wolter Mooi, VU University Amsterdam, and can be used free of charge. Kind regards, {my_name}

Slide sets

  • Common acquired naevus
  • Spitz naevus and variants
  • Blue naevus and variants
  • Congenital naevus
  • Dysplastic naevus
  • Nonmelanocytic skin lesions; some DD's
  • Melanoma: general features
  • Melanoma subtypes
  • Extracutaneous melanocytic lesions
  • Extracutaneous nonmelanocytic pigmented lesions
  • Problems and pitfalls

MELANOCYTE PATHOLOGY.COM information

Disclaimer | Privacy Statement | Cookies
Vrije Universiteit Amsterdam