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Clinical information

Female, 46 years of age. Small evenly pigmented macule, skin of buttock.

Show diagnosis & comments

Diagnosis:

Junctional melanocytic naevus.

Comments:

JUNCTIONAL NAEVI:

  • Nests ('theques') of naevus cells at the dermoepidermal junction, mostly located at or near tips of rete ridges
  • Sometimes associated lentiginous patterns of junctional naevus cells (i.e., arranged as solitary cells rather than producing nests)
  • Associated rete ridge elongation and epidermal hyperpigmentation
  • No cellular atypia
  • Generally no or little mitotitc activity
  • A few melanophages in the upper dermis are commonly present
  • Usually small lesion (a few mm) except near or in mucous membranes and, occasionally, acral skin
  • Most common in young individuals, but may arise later in life, and may persist for many years
Next case Return to the "Brief tour of naevi and melanomas" slide set
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Dear {friend_name}, {url} I believe this website may be of interest to you. It is an Open Educational Resource, containing a large collection of digitized histologic slides with explanatory films and other materials, aimed at surgical pathologists, dermatopathologist and pathologists in training. This site is entirely based on consultation materials of professor Wolter Mooi, VU University Amsterdam, and can be used free of charge. Kind regards, {my_name}

Slide sets

  • Naevus and melanoma: the essentials
  • Cutaneous melanocytes and their tumours
  • N or M? The basis of the distinction
  • So many naevus and melanoma variants! Split or lump?
  • Practical problems and pitfalls
  • Brief tour of naevi and melanomas

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